Nanobiosensors Based on Chemically Modified AFM Probes: A Useful Tool for Metsulfuron-Methyl Detection

Nanobiosensors Based on Chemically Modified AFM Probes: A Useful Tool for Metsulfuron-Methyl Detection

The use of agrochemicals has increased considerably in recent years, and consequently, there has been increased exposure of ecosystems and human populations to these highly toxic compounds. The study and development of methodologies to detect these substances with greater sensitivity has become extremely relevant. This article describes, for the first time, the use of atomic force spectroscopy ...

Modified AFM Probes for Nanoscale Biomolecular Recognition Studies

Biomolecular interactions are responsible for the initiation, modulation and termination of DNA replication, RNA transcription, enzyme activity, infection, immune response, tissue generation, wound healing, cellular differentiation, programmed cell death and the activities of drugs, hormones or toxic substances. AFM (atomic force microscopy) allows scientists to visualize, probe and analyze the...

Confidence-based scoring: a useful diagnostic tool for detection tasks

This paper uses an unconventional analysis as a tool to diagnose the problems with three different speech activity detection systems. The unconventional analysis is to score the frames in an audio file in order of confidence, starting with the frame that we have the most confidence in and progressing towards less and less confident frames. By keeping track of the cumulative number of errors, we...

Chemically Modified Electrodes for Detection of Pesticides

The Critical-Care Pain Observation Tool: A useful tool for pain assessment in intensive care units

Pain is a major concern in all intensive care units (ICUs). The proper assessment and management of pain is one of the main goals of patient care in ICUs. Improper evaluation of pain and its over or under treatment can cause significant problems in the process of patient management in ICU. Since most ICU patients are unable to communicate correctly with the ICU team and explain their level of p...